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If needed, refer to the Hepatic Insufficiency subsection of the Precautions section of this label for definitions of mild, moderate and severe hepatic impairment. The use of pilocarpine in patients with severe hepatic insufficiency is not recommended. Patients with mild hepatic insufficiency do not require dosage reductions. Regardless of the indication, the starting dose in patients with moderate hepatic impairment should be 5 mg twice daily, followed by adjustment based on therapeutic response and tolerability. SALAGEN® Tablets are indicated for 1) the treatment of symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for cancer of the head and neck and 2) the treatment of symptoms of dry mouth in patients with Sjogren's Syndrome. Inactive ingredients in the tablet, the tablet's film coating, and polishing are: carnauba wax, hypromellose, microcrystalline cellulose, stearic acid, titanium dioxide, FD&C blue#2 aluminum lake, and other ingredients. Inactive ingredients in the tablet, the tablet's film coating, and polishing are: carnauba wax, hypromellose, microcrystalline cellulose, stearic acid, titanium dioxide and other ingredients.Įach 7.5 mg SALAGEN® Tablet for oral administration contains 7.5 mg of pilocarpine hydrochloride. Pilocarpine hydrochloride, with a chemical name of (3S-cis)-2(3H)-Furanone, 3-ethyl-dihydro-4- mono-hydrochloride, has a molecular weight of 244.72.Įach 5 mg SALAGEN® Tablet for oral administration contains 5 mg of pilocarpine hydrochloride. Pilocarpine hydrochloride is a hygroscopic, odorless, bitter tasting white crystal or powder which is soluble in water and alcohol and virtually insoluble in most non-polar solvents. SALAGEN® Tablets contain pilocarpine hydrochloride, a cholinergic agonist for oral use. mental/mood changes (such as confusion, agitation), or.lung problems (such as increased wheezing/cough/phlegm),.Tell your doctor if you have unlikely but serious side effects of Salagen including: Tell your doctor if runny eyes become a problem. This can be helpful if you have dry eyes (such as with Sjogren's syndrome). redness of the face and neck (flushing),.Salagen (pilocarpine hydrochloride) is a cholinergic agonist that increases saliva secretion in the mouth used in the treatment of dry mouth. Find Lowest Prices on What is Salagen and how is it used?